- PERIARTICULAR HISTIOCYTIC SARCOMA
- Tufts University
- Periarticular istiocytic sarcoma is the most common tumor in joints of dogs, often filling the joint, crossing the joint space, and infiltrating the bone. Large breed dogs are most often affected, and Bernese mountain dogs rottweilers are overrepresentied. There appears to be a significant association between previous joint disease/trauma and periarticular histiocytic sarcoma, especially previous cruciate repair. Neoplastic cells are often CD1a, CD11c/CD18 positive. metastatic disease has been identified in 91% of dogs with followup in one study.