Charles Louis Davis and Samuel Wesley Thompson DVM Foundation

For the Advancement of Veterinary and Comparative Pathology

info@cldavis.org | Phone: 847-367-4359 | Fax: 847-247-1869

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Image: F30175

Pathology Image
  • SPECIES:
    • BOVINE
  • SYSTEM:
    • NERVOUS
  • ORGAN:
    • CEREBRUM
  • DIAGNOSIS:
    • SEVERE DIFFUSE CEREBRAL CONGESTION
  • CAUSE:
    • BABESIA BOVIS
  • CONTRIBUTOR:
    • RICARDO MENDES
  • INSTITUTION:
    • INSTITUTO FEDERAL CATARINENSE - IFC
  • GENPATH:
    • PROTOZOA
  • COMMENTS:
    • Tissue from a 2-year-old Friesian cow. B. bovis causes the most severe form of babesiosis in cattle in which peripheral circulatory disturbances with sequestration of parasitized erythrocytes in the peripheral circulation are unique features. In southern Brazil this form of disease is found in approximately two-thirds of the cases of babesiosis caused by B. bovis and is virtually always fatal. Necropsy findings include yellow discoloration (icterus) of mucosae, subcutaneous tissue, muscle fasciae and the intimal surface of arteries. In acute or peracute cases (which include the cases of cerebral babesiosis) icterus can be mild or absent. The serosal membranes of the abdominal viscera have hemoglobin imbibition. The liver is swollen, with rounded edges, and is yellow or tan discolored. The biliary vesicle is usually markedly distended by dark-green inspissated bile. Subepicardial and subendocardial hemorrhages (petechiae and ecchymosis) are virtually always observed. In cases where hemoglobinuria is a prominent sign, the kidneys are diffusely dark red-brown (hemoglobinuric nephrosis) and the urine is dark-red (red water disease). There is always some degree of splenomegaly. In severely enlarged spleens the red pulp prolapses on the cut surface. In cerebral babesiosis, the grey matter of the telencephalic, and cerebellar cortex and that of the basal nuclei has a characteristic cherry pink color. Squashes made from cortical brain, stained with Wright-Giemsa reveal numerous capillaries engorged with parasitized erythrocytes.