Charles Louis Davis and Samuel Wesley Thompson DVM Foundation

For the Advancement of Veterinary and Comparative Pathology

info@cldavis.org | Phone: 847-367-4359 | Fax: 847-247-1869

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  • SPECIES:
    • BOVINE
  • SYSTEM:
    • SKELETAL
  • ORGAN:
    • BODY AS A WHOLE
  • DIAGNOSIS:
    • ARTHROGRYPOSIS
  • CONTRIBUTOR:
    • SCHUMACHER
  • INSTITUTION:
    • Iowa State University
  • GENPATH:
    • VIRAL
  • COMMENTS:
    • Causes: a) Akabane virus (Bunyavirus) b) BVDV virus (Pestivirus) c) Cache valley fever (Bunyavirus) d) Lupinus laxiflorus (wild lupine) e) Schmallenberg virus (Salient Lesions in Domestic Ruminants infected with emerging so-called Schmallenberg virus in Germany, Vet path. 2012) 3. Pathogenesis: intrauterine viral infection damage to fetal CNS degeneration/atrophy of muscles with contraction of limbs Or: Maternal intoxication of lupine (anagyrine)fetal paralysisdegeneration/atrophy of muscles with contraction of limbs ---PBVD p. 964 This fetus also had a cleft palate which can be seen in certain breeds of cattle (Charolais, Friesian, Swedish and Red Danish) with arthrogyposis. (Jubb Vol. 1 p. 206) however genetic testing was negative for arthrogryposis muliplex in this case. We did see mild myelodysplasia which likely played a role in the development of lesions.