- URINARY BLADDER
- NECROTIZING AND HEMORRHAGIC CYSTITIS
- Armed Forces Institute of Pathology
- Sterile cystitis is the most common and dose-dependent sequelae of cyclophophamide chemotherapy. Acrolein, the toxic principle, directly damages the bladder mucosa. Symptoms may be seen during or following the course of treatment. Diuresis with or without concurrent 2 mercaptoethane sulphone sodium administration may lessen the incidence of dogs under treatment.